Anti-IL2 Rat Monoclonal Antibody (PE (Phycoerythrin)) [clone: JES6-5H4]

Dodavatel: Tonbo Biosciences
50-7021-U025EA 1260 CZK
50-7021-U025 50-7021-U100
Anti-IL2 Rat Monoclonal Antibody (PE (Phycoerythrin)) [clone: JES6-5H4]
The JES6-5H4 antibody binds to mouse Interleukin-2 (IL-2), a 17 kDa cytokine that is secreted by activated T cells. This cytokine acts as an autocrine stimulatory factor for T cell proliferation, differentiation and survival, as well as being an effective activator of B cells and inducer of NK cell cytotoxic functions. IL-2 plays a key modulatory role in the differentiation of T cells toward either Th17 or T regulatory (Treg) cell types and is important for Treg cell function. The IL-2 receptor (IL-2R) is a complex consisting of an IL-2R alpha chain (CD25), along with the IL-2R beta chain (CD122) and the common gamma chain (CD132). IL-2 may also bind with low affinity to the T cell surface protein CD25 alone, although this interaction does not induce cell signaling.

Type: Primary
Antigen: IL2 (interleukin 2)
Clonality: monoclonal
Clone: JES6-5H4
Conjugation: PE (Phycoerythrin)
Host: Rat
Isotype: IgG2b Kappa
Reactivity: Mouse

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