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Anti-AANAT Rabbit Polyclonal Antibody

Dodavatel: Thermo Fisher Scientific
PIEAPA116522EA 0 CZK
PIEAPA116522
Anti-AANAT Rabbit Polyclonal Antibody
Protilátky
This antibody does not react with rat, bovine, chicken or zebrafish samples. Arylalkylamine N-Acetyltransferase (AANAT) is the penultimate enzyme is melatonin synthesis. Hormonal melatonin has been implicated in sleep and circadian clock function. Large changes in the abundance of AANAT are believed to be responsible for the large day/night rhythms in melatonin synthesis in the pineal gland and retina (1,2). Most research shows that AANAT activity is regulated by controlling the steady-state levels of the protein. Recent research, however, suggests that another mechanism may also play a role in controlling melatonin production without altering AANAT protein and activity. This mechanism may explain the sudden physiological increase in circulating melatonin observed at the onset of the dark period in humans.

Type: Primary
Antigen: AANAT
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Primates, Human
Objednat

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