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Anti-TACR1 Rabbit Polyclonal Antibody

Dodavatel: Thermo Scientific
The target sequence has 92% sequence homology with canine. The tachykinins belong to an evolutionary conserved family of peptide neurotransmitters that share the c-terminal sequence Phe-X-Gly-Leu-Met-NH2 and have an established role in neurotransmission. The mammalian tachykinins include substance P, neurokinin A (NKA) and neurokinin B (NKB) which exert their effects by binding to specific receptors. Tachykinin peptides are important in the mediation of many physiological and pathological processes including inflammation, pain, migraine headache and allergy induced asthma. Three tachykinin receptor types have been characterized, NK-1, NK-2 and NK-3 which have preferential affinities for SP, NKA and NKB respectively. All three receptors share a high degree of sequence homology, have seven transmembrane spanning domains and similar signal transduction mechanisms (e.g. G-protein coupled activation of phospholipase C).

Type: Primary
Antigen: TACR1
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Guinea Pig, Human, Mouse, Rat




 

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Rozměry protilátky Bal. VWR katalogové číslo Množství
100 µL 100 µl PIEAPA116713 Blocked
Blocked Tento produkt je zablokován vaší organizací. Kontaktujte své nákupní oddělení pro více informací.
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Produktová specifikace

Symbol antigenu TACR1
Název antigenu Substance P Receptor
Reaktivita Rat, Human, Mouse, Guinea Pig
Spojení Unconjugated
Klonovalita Polyclonal
Druh protilátky Primary
Hostitel Rabbit
Isotyp IgG
Western blot Yes
Imunochemie Yes
Imunofluorescence Yes
Synonyma antigenu NK1 receptor, TAC1R, Substance P receptor, SPR, Tachykinin receptor 1, NK1R, TACR1
Identifikační číslo genu 24807, 100135626, 6869, 21336
Formát whole serum
Imunogen Raised against a synthetic peptide at the c-terminus of rat NK-1 conjugated to bovine thyroglobulin.
Forma Liquid
Skladovací pufr whole serum, no preservative
Skladovací teplota -20° C, Avoid Freeze/Thaw Cycles
Transportní teplota Ice
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