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Anti-TACR3 Rabbit Polyclonal Antibody

Dodavatel: Thermo Scientific
This antibody does not react with human samples and is not recommended for Western blot. The tachykinins belong to an evolutionary conserved family of peptide neurotransmitters that share the c-terminal sequence Phe-X-Gly-Leu-Met-NH2 and have an established role in neurotransmission. The mammalian tachykinins include substance P, neurokinin A (NKA) and neurokinin B (NKB) which exert their effects by binding to specific receptors. Tachykinin peptides are important in the mediation of many physiological and pathological processes including inflammation, pain, migraine headache and allergy induced asthma. Three tachykinin receptor types have been characterized, NK-1, NK-2 and NK-3 which have preferential affinities for SP, NKA and NKB respectively. All three receptors share a high degree of sequence homology, have seven transmembrane spanning domains and similar signal transduction mechanisms (e.g. G-protein coupled activation of phospholipase C).

Type: Primary
Antigen: TACR3
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
Isotype: IgG
Reactivity: Mouse, Rat, Ovine, Guinea Pig



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Rozměry protilátky Bal. VWR katalogové číslo Množství
150 µL 150 µl PIEAPA116714 Blocked
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Produktová specifikace

Symbol antigenu TACR3
Název antigenu Neurokinin B Receptor
Reaktivita Ovine, Mouse, Rat, Guinea Pig
Spojení Unconjugated
Klonovalita Polyclonal
Druh protilátky Primary
Hostitel Rabbit
Isotyp IgG
Imunochemie Yes
Imunofluorescence Yes
Synonyma antigenu Tachykinin receptor 3, TACR3, Neuromedin K Receptor, TAC3RL, Neurokinin B receptor, NK3 receptor, NK3R TAC3R
Identifikační číslo genu 24808, 21338, 100135627
Formát whole serum
Imunogen Raised against a synthetic peptide at the c-terminus of rat NK-3 conjugated to bovine thyroglobulin.
Form Liquid
Skladovací pufr whole serum, 0.1% sodium azide
Skladovací teplota -20° C, Avoid Freeze/Thaw Cycles
Transportní teplota Ice
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