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Anti-CENPF Rabbit Polyclonal Antibody

Dodavatel: Thermo Scientific
Suggested positive control: HeLa and SK-N-SH cells. The kinetophore is a macromolecular structure that is associated with the centromeres of chromosomes and is responsible for establishing and maintaining the connections with the microtubules of the mitotic spindle. The proteins that reside within the chromosomal domain fall into two broad classes: those that associate with the centromere throughout the cell cycle and those that are found at the centromere in a cell cycle specific manner. Members of the first class include CENP-A, CENP-B, and CENP-C. The members of the second class include several ubiquitous cellular proteins such as calmodulin, tubulin, dynein and p34 cdc2 and also CENP-E and CENP-F. CENP-F appears to be the earliest member to interact with the centromere-kinetochore complex. CENP-F also shows a cell-cycle distribution that is both temporally regulated and diverse in terms of the structural components it localizes to and therefore may play a role in several mitotic events.

Type: Primary
Antigen: CENPF
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Bovine



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OBJEDNÁVKA

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50 µL 50 µl PIEAPA116826 Blocked
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TECHNICKÉ ÚDAJE

Symbol antigenu CENPF
Název antigenu Centromere Protein F, 350/400kDa
Reaktivita Bovine, Human
Spojení Unconjugated
Klonovalita Polyclonal
Druh protilátky Primary
Hostitel Rabbit
Isotyp IgG
Western Blot Yes
Imunoprecipitace Yes
Imunofluorescence Yes
Průtoková cytometrie Yes
Synonyma antigenu Centromere Protein F, CENPF, AH Antigen, CENF, CENP F Kinetochore Protein, Mitosin
Gene ID 1063
Koncentrace 2.5 mg/ml
Imunogen A bacterial fusion protein from the C-terminus of CENP-F.
Čištění Affinity chromatography
Forma Liquid
Skladovací pufr PBS, 50% glycerol, 0.05% sodium azide
Skladovací teplota -20° C, Avoid Freeze/Thaw Cycles
Transportní teplota Ice
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