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Anti-Calreticulin Rabbit Polyclonal Antibody

Dodavatel: Thermo Scientific
PA1-16924 is specific for the ~55 kDa Calreticulin protein. There are also several reported isoforms that range from 48-62 kDa. Suggested positive control: antigen standard for CALR (transient overexpression lysate). Calreticulin is a multifunctional, highly conserved Ca2+ -binding protein that is localized to the endoplasmic reticulum (ER). It is also a molecular chaperone and is involved in protein folding events in the ER. Calreticulin has also been shown to interact with the cytoskeleton and to be involved in the regulation of gene expression. Calreticulin may play a role in cellular proliferation including its apparent activity in the proliferation of certain viruses within mammalian host cells. Recently it has been shown that calreticulin is induced in response to various types of cell stress including amino acid deprivation. Close interconnections among protein synthesis, gene expression and calcium signaling have been observed by many researchers in recent years. Calreticulin might be centrally located and crucially participate in the coordination of these functions by the cell.

Type: Primary
Antigen: Calreticulin
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse



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OBJEDNÁVKA

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Rozměry protilátky Bal. VWR katalogové číslo Množství
100 µL 50 µl PIEAPA116924 Blocked
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TECHNICKÉ ÚDAJE

Symbol antigenu Calreticulin
Název antigenu Calreticulin
Reaktivita Mouse, Human
Spojení Unconjugated
Klonovalita Polyclonal
Druh protilátky Primary
Hostitel Rabbit
Isotyp IgG
Western Blot Yes
Imunochemie Yes
Imunofluorescence Yes
Synonyma antigenu Autoantigen RO antibody, CALR antibody.
Gene ID 12317, 811
Formát whole serum
Imunogen Full length native mouse Calreticulin protein.
Forma Liquid
Skladovací pufr whole serum, 0.1% sodium azide
Skladovací teplota Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Transportní teplota Ice
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