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Anti-LC3 Rabbit Polyclonal Antibody

Dodavatel: Thermo Scientific
The reaction with mouse LC3 is weaker than human. The immunogen for this antibody production has 100% sequence homology with rat and zebrafish, 92% with mouse, and 91% with bovine proteins. LC3, a mammalian homologue of Apg8, was originally identified as microtubule-associated protein 1 light chain 3. It is a component of both the MAP1A and MAP1B microtubule-binding domains and the heavy-chain independent regulation of LC3 expression might modify MAP1 microtubule-binding activity during development. However, LC3 is now thought to also be involved in autophagy. LC3-I is cytosolic and LC3-II is membrane bound and enriched in the autophagic vacuole fraction. LC3-II is the first mammalian protein identified that specifically associates with the autophagosome membranes.

Type: Primary
Antigen: LC3
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Hamster, Primates, Canine, Bacteria, Bovine, Human, Rat, Porcine, Mouse, Zebrafish



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OBJEDNÁVKA

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100 µL 100 µl PIEAPA116930 Blocked
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TECHNICKÉ ÚDAJE

Symbol antigenu LC3
Název antigenu 1A/1B-light chain 3
Reaktivita Bovine, Porcine, Dog, Mouse, Primates, Zebrafish, Hamster, Bacteria, Rat, Human
Spojení Unconjugated
Klonovalita Polyclonal
Druh protilátky Primary
Hostitel Rabbit
Isotyp IgG
Western Blot Yes
ELISA Yes
Imunochemie Yes
Imunoprecipitace Yes
Imunofluorescence Yes
Synonyma antigenu MAP1A/b light chain 3 B antibody, MAP1 light chain 3-like protein 2 a, Microtubule-associated proteins 1A/1B light chain 3B MAP1A/MAP1B LC3 B antibody
Gene ID 81631, 322425, 408001, 67443, 64862, 100462754
Koncentrace 1 mg/ml
Imunogen Synthetic peptide between amino acids 1-100 of the human LC3 protein.
Čištění Antigen affinity chromatography
Forma Liquid
Skladovací pufr PBS, 0.02% sodium azide
Skladovací teplota -20° C, Avoid Freeze/Thaw Cycles
Transportní teplota Ice
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