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Anti-CLIP1 Goat Polyclonal Antibody

Dodavatel: Thermo Scientific
This antibody is predicted to react with canine, mouse, porcine and rat based on sequence homology. CLIP170 was initially identified as a new type of intermediate filament associated protein that is highly expressed in Reed-Sternberg cells, the tumoral cells diagnostic for Hodgkin's disease. Later experiments showed that it is located at microtubule plus ends and is required for the binding of endocytic carrier vesicles. CLIP170 has also been suggested to act with LIS1, a protein implicated in brain development, to regulate dynein/dynactin binding microtubules. Other studies suggest that CLIP170 can influence the formation of lamellipodia and cell invasion by invasive breast cancer cells by regulating the release of kinesin and IQGAP1 from a complex of those proteins, CLIP170 and Rac1. At least two isoforms of CLIP170 are known to exist.

Immunohistochemistry: 2-4µg/ml, Western Blot: 1-3 ug/ml

Type: Primary
Antigen: CLIP1
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Goat
Isotype: IgG
Reactivity: Human



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OBJEDNÁVKA

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Rozměry protilátky Bal. VWR katalogové číslo Množství
100 ug 100 µG PIEAPA519167 Blocked
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TECHNICKÉ ÚDAJE

Symbol antigenu CLIP1
Název antigenu CAP-GLY Domain containing linker Protein 1
Reaktivita Human
Spojení Unconjugated
Klonovalita Polyclonal
Druh protilátky Primary
Hostitel Goat
Isotyp IgG
Western Blot Yes
Imunochemie Yes
Synonyma antigenu RSN, CYLN1, restin, CAP-GLY domain containing linker protein 1, CLIP170, Reed-Steinberg cell-expressed intermediate filament-associated protein, cytoplasmic linker 1, CLIP-170, CLIP, MGC131604, CLIP1, restin (Reed-Steinberg cell-expressed intermediate filament-associated protein)
Gene ID 6249
Koncentrace 0.5 mg/ml
Imunogen Synthetic peptide sequence (PHSTHHGSRGEERP) corresponding to the C-terminus amino acids of CLIP1
Čištění Antigen affinity chromatography
Forma Liquid
Skladovací pufr TBS, 0.5% BSA, 0.02% sodium azide, pH 7.3
Skladovací teplota -20° C, Avoid Freeze/Thaw Cycles
Transportní teplota Ice
Název značky Invitrogen
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