Anti-TLR2 Mouse Monoclonal Antibody [clone: BV31-9]

Dodavatel: BioVision
BIOV3569-100EA 8320 CZK
Anti-TLR2 Mouse Monoclonal Antibody [clone: BV31-9]
The Toll-like receptor (TLR) family in mammalian comprises a family of transmembrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and IL-1 receptor motif in the cytoplasmic domain. Up-to-date, ten TLRs (TLR1-10) have been described. TLR2 is differentially expressed in human cells. CD14+ monocytes expressed the highest level of TLR2 followed by CD15+ granulocytes, and CD19+ B-cells. CD3+ T-cells and CD56+ NK cells did not express TLR2. The expression of TLR2 on different cell types are regulated by different immune response modifiers. For example, LPS, GM-CSF, IL-1, and IL-10 up regulate TLR2, whereas IL-4, IFN-gamma, and TNF down regulate TLR2 expression in monocytes.

Recommended Dilutions: Western Blot: 1:200-1000

Type: Primary
Antigen: TLR2
Clonality: Monoclonal
Clone: BV31-9
Conjugation: Unconjugated
Host: Mouse
Isotype: IgG1
Reactivity: Human

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