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Anti-Wnt-6 Rabbit Polyclonal Antibody

Dodavatel: BioVision
BIOV3570-100EA 6910 CZK
BIOV3570-100
Anti-Wnt-6 Rabbit Polyclonal Antibody
Protilátky
Wnt gene family members, including Wnt-1 throμgh Wnt-10, play a key role in regulating cellular growth and differentiation. Wnt-1 is a cysteine-rich, secreted glycoprotein that associates with cell membranes and likely functions as a key regulator of cellular adhesion. Wnt-1, which is essential for normal development of the embryonic nervous system, contributes to hyperplasia and tumorigenic progression when improperly expressed in mammary tissue. Wnt-3 is involved in tumorigenesis and Wnt-2 and Wnt-4 may be associated with abnormal proliferation in human breast tissue. Wnt-6 is involved in oncogenesis and is co-expressed with Wnt10 in colorectal cancer cell lines. The presence of cervical and breast cell carcinomas may indicate an over expression of Wnt-6.

Recommended Dilutions: Western Blot: 0.5-4 µg/ml; Immunohistochemistry: 10-20 µg/ml

Type: Primary
Antigen: Wnt-6
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
Objednat

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