Anti-Phospho-JNK/SAPK Rabbit Polyclonal Antibody

Dodavatel: BioVision
BIOV3589-100EA 9170 CZK
Anti-Phospho-JNK/SAPK Rabbit Polyclonal Antibody
The JNK pathway is activated by largely distinct stimuli including inflammatory cytokines (such as TNF-α and IL-1), UV light, inhibitors of protein synthesis and osmotic stress. Activated MEKK1 phosphorylates SEK1 (also known as MKK4), which in turn activates SAPK (also known as JNK;JNK binds tightly to the N-terminal region of c-Jun and ATF-2, and phosphorylates c-Jun at Ser63 and Ser73 and ATF-2 at Thr69 and Thr71.

Recommended Dilutions: Western Blot: 1-2 µg/ml; Immunoprecipitation: 10-20 µg/ml; Immunocytochemistry: 10-20 µg/ml; and Immunohistochemistry: 20-30 µg/ml

Type: Primary
Antigen: Phospho-JNK/SAPK
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat

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