Anti-ASK1/MAPKKK5 Rabbit Polyclonal Antibody

Dodavatel: BioVision
BIOV3128-100EA 7470 CZK
Anti-ASK1/MAPKKK5 Rabbit Polyclonal Antibody
ASK1 (Apoptosis Signal-regulating Kinase 1) activates two different subgroups of MAPKK, MKK4 and MKK6, which in turn activate c-Jun N-terminal Kinase (JNK) and p38 MAP Kinase. ASK1 is activated by TNFR and Fas throμgh the interaction with members of the TRAF Family and the Fas-associated protein Daxx. Overexpression of ASK1 induces apoptosis. However, a catalytically inactive form of ASK1 has been shown to inhibit TNF-α induced apoptosis.

Recommended Dilutions: Western Blot: 1-4 µg/ml

Type: Primary
Antigen: ASK1/MAPKKK5
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
Isotype: IgG
Reactivity: Human

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