Anti-Gai2 Rabbit Polyclonal Antibody

Dodavatel: BioVision
BIOV3249-100EA 6910 CZK
Anti-Gai2 Rabbit Polyclonal Antibody
Gαi2 is a 40-41 kDa alpha-subunit of heterotrimeric protein that shares sequence homology with Gαi3 and Gαi1. All these G proteins can be ADP-ribosylated at the carboxy terminal Cys of the CAAX sequence, interfering with receptor coupling. Gαi2 is expressed widely in tissues and cell lines. Activation of PLC-β by Gαi-coupled receptors is the result of release of Gβg subunits from Gαi. Gαi2 regulates potassium channel activation. Mutation at Arg179 has been identified in tumors. This and the Q205L mutant inhibit adenylyl cyclase.

Recommended Dilutions: Western Blot: at 0.5-4 µg/ml; immunoprecipitation

Type: Primary
Antigen: Gai2
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
Isotype: IgG
Reactivity: Human

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