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Anti-TLR4 Rabbit Polyclonal Antibody

Dodavatel: BioVision
BIOV3251-100EA 7470 CZK
BIOV3251-100
Anti-TLR4 Rabbit Polyclonal Antibody
Protilátky
TLR4 (Toll-like receptor 4) is a mammalain homologue of the Drosophila toll protein. The human TLR4 is a type-1 transmembrane protein containing 799 amino acid residues. The extracellular domain has leucine-rich repeats and the intracellular domain is similar to that of IL-1 receptor. TLR4 is a receptor for lipopolysaccharide (LPS;In mice that are genetically tolerant to endotoxin, mutations have been identified in the intracellular domain of TLR4 that abolish LPS responsiveness. TLR4 uses a mechanism similar to that of the IL-1 receptor for signal transduction that leads to activation of NF-kB.

Recommended Dilutions: Western Blot: 0.5-4 µg/ml;The antibody is also suitable for flow cytometric analysis of cell surface expression of TLR4

Type: Primary
Antigen: TLR4
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human
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