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Anti-Calreticulin Mouse Monoclonal Antibody [clone: S75]

Dodavatel: BioVision
BIOV3076-100EA 8740 CZK
BIOV3076-100
Anti-Calreticulin Mouse Monoclonal Antibody [clone: S75]
Protilátky
Calreticulin is a calcium binding protein found in abundance in the endoplasmic reticulum and the sarcoplasmic reticulum. Like many other ER proteins, it has the conserved ER retention KDEL (Lys-Asp-Glu-Leu) sequence at its C-terminus. Calreticulin has also been detected in the nucleus and nuclear envelop. Recent studies sμggest that this soluble ER protein has a multifunctional role as it appears to be involved in calcium storage and regulation as well as having a molecular chaperone activity. Studies also sμggest its involvement in certain autoimmune diseases. Consistence with its multiple functions the calreticulin molecule appears to have a zonal character. The protein has both high and low affinity calcium binding sites.

Recommended Dilutions: Western Blot: 0.5-4 µg/ml

Type: Primary
Antigen: Calreticulin
Clonality: Monoclonal
Clone: S75
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG1
Reactivity: Human, Mouse, Rat
Objednat

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