Anti-Cathepsin B Rabbit Polyclonal Antibody

Dodavatel: BioVision
BIOV3190-100EA 7470 CZK
Anti-Cathepsin B Rabbit Polyclonal Antibody
Cathepsin B is a normal lysosomal cysteine proteinase that is expressed in all cells. It is synthesized as an inactive 43 kDa pro-enzyme which, by removal of a 62 amino acid propeptide, is activated to the single-chain form of 31 kDa or the two-chain form (25 and 5 kDa subunits;Matured cathepsin B is normally localized in the lysosomes where it functions in protein turnover. Cathepsin B is also shown capable of degrading extracellular matrix proteins. Elevated levels of cathepsin B correlate with malignancy sμggesting that this enzyme may be a useful prognostic marker for several types of human cancers.

Recommended Dilutions: Western Blot: 0.5-4 µg/ml) amd in Immunohistochemistry: 10-20 µg/ml

Type: Primary
Antigen: Cathepsin B
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
Isotype: IgG
Reactivity: Human

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