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Anti-Proteinase Inhibitor 9 Rabbit Polyclonal Antibody

Dodavatel: BioVision
BIOV3544R-100EA 6910 CZK
BIOV3544R-100
Anti-Proteinase Inhibitor 9 Rabbit Polyclonal Antibody
Protilátky
Proteinase inhibitor 9 (PI-9, also designated cytoplasmic antiproteinase 3, or CAP3) is a 42 kDa member of the ovalbumin family of serpins that is expressed in placenta, lung and cytotoxic lymphocytes. PI-9 is a potent inhibitor of granzyme B and of granzyme B-mediated apoptosis, and is also an inhibitor of capase-1 and, to a smaller extent, caspase-4 and caspase-8. PI-9 expression is also upregulated in response to inflammatory stimuli. This upregulation protects cells from apoptosis induced by endogenously expressed or released granzyme B, particulary during target cell killing

Recommended Dilutions: Western Blot: 1-4 µg/ml

Type: Primary
Antigen: Proteinase Inhibitor 9
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope: N-terminal
Host: Rabbit
Isotype: IgG
Reactivity: Human
Objednat

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