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Anti-TLR8 Mouse Monoclonal Antibody [clone: 44B05]

Dodavatel: BioVision
BIOV3558-100EA 9730 CZK
BIOV3558-100
Anti-TLR8 Mouse Monoclonal Antibody [clone: 44B05]
Protilátky
The Toll-like receptor (TLR) family of proteins are characterized by a highly conserved Toll homology (TH) domain, which is essential for Toll-induced signal transduction. TLR1 contains an extracellular domain consisting of several leucine-rich regions along with a single cytoplasmic Toll/IL-1R-like domain. TLR2 and TLR4 are activated in response to lipopolysacchride (LPS) stimulation, which results in the activation and translocation of NFkB and sμggests that these receptors are involved in mediating inflammatory responses. TLR6 is highly homologous to TLR1, and like other members of TLR family, it induces NFkB signaling upon activation. TLR8 gene contains three exons, two of which have coding function. Expression of TLR receptors is highest in peripheral blood leukocytes, macrophages, and monocytes.

Recommended Dilutions: Western Blot: 1:200-1000 dilutions

Type: Primary
Antigen: TLR8
Clonality: Monoclonal
Clone: 44B05
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG1
Reactivity: Human
Objednat

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