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Anti-AMPK alpha 2 Rabbit Polyclonal Antibody

Dodavatel: BioVision
BIOV3117-100EA 9170 CZK
BIOV3117-100
Anti-AMPK alpha 2 Rabbit Polyclonal Antibody
Protilátky
The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK;AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart sμggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia.

Recommended Dilutions: ELISA: 0.25 µg/ml; Western Blot: 2.5-5.0 µg/ml; Immunohistochemistry: 5-25 µg/ml).

Type: Primary
Antigen: AMPK alpha 2
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope: C-terminal
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse
Objednat

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