HNF4A is a nuclear transcription factor which binds DNA as a homodimer. This protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This protein may play a role in development of the liver, kidney, and intestines. Mutations in the HNF4A gene have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I.
Recommended Dilutions: ELISA: 0.25 ?g/ml; Western Blot: 2.5-5.0 ?g/ml; Iimmunofluorescence: 1:10-1:50; Flow Cytometry: 1:10-1:50).