Anti-APP Rabbit Polyclonal Antibody

Dodavatel: BioVision
BIOV6001-100EA 7470 CZK
Anti-APP Rabbit Polyclonal Antibody
Accumulation of the amyloid-β peptide (Aβ) in the cerebral cortex is a critical event in the pathogenesis of Alzheimer’s disease. The β-amyloid protein precursor (APP) is cleaved by β-secretase, producing a soluble derivative of the protein and a membrane anchored 99-amino acid carboxy-terminal fragment (C99;The C99 fragment serves as substrate for g-secretase to generate the 4 kDa amyloid-β peptide, which is deposited in the brains of all suffers of Alzheimer’s disease.

  • Recommended Dilutions: Western Blot: 1-4 µg/ml; Immunohistochemistry: 2-10 ug/ml

Type: Primary
Antigen: APP
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat

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