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Anti-USP34 Core Chicken Polyclonal Antibody

Dodavatel: BioVision
BIOV6136-50EA 4090 CZK
BIOV6136-50
Anti-USP34 Core Chicken Polyclonal Antibody
Protilátky
USP34 Core is a ubiquitin hydrolase that can remove conjugated ubiquitin from AXIN1 and AXIN2, thereby acting as a regulator of Wnt signaling pathway. It acts as an activator of the Wnt signaling pathway downstream of the beta-catenin destruction complex by deubiquitinating and stabilizing AXIN1 and AXIN2, leading to promote nuclear accumulation of AXIN1 and AXIN2 and positively regulate beta-catenin (CTNBB1)-mediated transcription. It recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. It is involved in the processing of poly-ubiquitin precursors as well as that of ubiquinated proteins. Its catalytic core consists of residues 1892-2241.

Recommended Dilutions: Western Blot: Robust detection of 100 ng of recombinant protein was possible when antibody was used at a final concentration of 5 ?g/mL

Type: Primary
Antigen: USP34 Core
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Chicken
Isotype: IgG
Reactivity: Human
Objednat

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