Anti-Rho Kinase Alpha Rabbit Polyclonal Antibody

Dodavatel: BioVision
BIOV3789-100EA 9730 CZK
Anti-Rho Kinase Alpha Rabbit Polyclonal Antibody
Rho-associated protein kinase 2 (ROCK2), or Rho kinase alpha, is a serine-threonine protein kinase that plays an important role in cellular apoptosis, growth, cell motility and cell contraction. ROCK2 shares an overall 65% homology in amino acid sequence with ROCK1. The ROCK1 and ROCK2 isoforms are products of two separate genes. Both ROCK1 and ROCK2 are downstream targets of the Rho A small GTP-binding protein. As downstream effectors of RhoA, ROCK1 and ROCK2 mediate changes in the actin cytoskeleton via phosphorylation of target proteins such as the MBS subunit of MLCP, MLC, ERM proteins, protein LIM kinase and adducin.

Recommended Dilutions: Western Blot: 1:1000-1:2500; Immunoprecipitation

Type: Primary
Antigen: Rho Kinase Alpha
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse

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