Anti-Glutathione Reductase Mouse Monoclonal Antibody [clone: 2B3]

Dodavatel: BioVision
BIOV6212-100EA 9170 CZK
Anti-Glutathione Reductase Mouse Monoclonal Antibody [clone: 2B3]
Glutathione reductase (GR) is a member of pyridine nucleotide-disulfide oxidoreductases, which includes the closely related enzymes thioredoxin reductase, lipoamide dehydrogenase, trypanothione reductase and mercuric ion reductase. GR is a cytoplasmic flavoenzyme widely distributed in aerobic organisms. The dimeric protein is composed of two identical subunits, each containing 1 FAD and 1 redox-active disulfide/dithiol as components of the catalytic apparatus. It plays a role in maintaining glutathione (GSH) in its reduced form by catalyzing the reduction of glutathione disulfide (GSSG;In most eukaryotic cells, GR maintains the ratio of [GSH]/[GSSG] elevated, and participates in several vital functions such as the detoxification of reactive oxygen species as well as protein and DNA biosynthesis.

Recommended Dilutions: IP: 1-2 µl, ELISA.

Type: Primary
Antigen: Glutathione Reductase
Clonality: Monoclonal
Clone: 2B3
Conjugation: Unconjugated
Host: Mouse
Isotype: IgG1
Reactivity: Human

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