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Anti-Aldolase C Rabbit Polyclonal Antibody

Dodavatel: BioVision
BIOV6756-100EA 6910 CZK
BIOV6756-100
Anti-Aldolase C Rabbit Polyclonal Antibody
Protilátky
Fructose 1, 6-bisphosphate aldolase catalyses the reversible condensation of glycerone-P and glyceraldehyde 3-phosphate into fructose 1, 6-bisphosphate. Fructose 1, 6-bisphosphate aldolase exists as three forms, the muscle-specific Aldolase A, the liver-specific aldolase B, and the brain-specific aldolase C. Aldolase A, B, and C arose from a common ancestral gene, from which aldolase B first diverged. Aldolase A is one of the most highly conserved enzymes known, with only about 2% of the residues changing per 100 million years. Aldolase B is regulated by the hormones insulin and glucagon and has been implicated in hereditary fructose intolerance disease. Aldolase C is a polypeptide that is exclusively expressed in Purkinje cells. Aldolase C-positive Purkinje cells are organized in the cerebellum as stripes or bands that run from anterior to posterior across the cerebellum and alternate with bands of Aldolase C-negative Purkinje cells.

Recommended Dilutions: Western Blot: ~1:1000, IHC: ~1:10-1:50.

Type: Primary
Antigen: Aldolase C
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope: C-terminal
Host: Rabbit
Isotype: IgG
Reactivity: Human. Predicted Cross Reactivity With Mouse, Rat And Monkey Samples.
Objednat

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