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Anti-C-Kit/CD117 Rabbit Polyclonal Antibody

Dodavatel: BioVision
BIOV6777-100EA 6910 CZK
BIOV6777-100
Anti-C-Kit/CD117 Rabbit Polyclonal Antibody
Protilátky
The c-Kit proto-oncogene is a member of the receptor tyrosine kinase family and, more specifically, is closely related to the platelet derived growth factor receptor (PDGFR;c-Kit, the normal cellular homolog of the HZ4-feline sarcoma virus transforming gene (v-Kit), encodes a transmembrane receptor. c-Kit regulates a variety of biological responses including chemotaxis, cell proliferation, apoptosis, and adhesion. c-Kit is also identical with the product of the W locus in mice and, as such, is integral to the development of mast cells and hematopoiesis. The ligand for the c-Kit receptor (KL) has been identified and is encoded at the murine steel (SI) locus. Kit is the human homolog of the proto-oncogene c-Kit. Mutations in Kit are integral for tumor growth and progression in various cancers.

Recommended Dilutions: Western Blot: 1:1000, IHC: 1:10-1:50, Immunofluorescence: 1:10-1:50.

Type: Primary
Antigen: C-Kit/CD117
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope: N-terminal
Host: Rabbit
Isotype: IgG
Reactivity: Human.
Objednat

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