Amyloid Beta (Aβ or Abeta) is a multi-functional peptide of 36-43 amino acids, processed from the Amyloid Precursor Protein (APP;It is most commonly known to be associated with Alzheimer's disease since it is the main component of amyloid plaques found in the brains of the diseased subjects. However, it also plays a role in multiple non-disease activities including protection against metal-induced reactive oxidizing species (ROS), modification of cholesterol transport, and potential activity as a transcription factor. It is secreted by platelets into the blood serum and its levels elevate with age.
Recommended Dilutions: Immunohistochemistry: 40-150 µg. However, optimal conditions must be determoned by the user.
Antigen: Amyloid beta 1-17
Reactivity: Human. The 1-13 Amino Acid Sequence Of This Protein Is Conserved In Mice, Rat, Humans And Other Species, So It Might Cross-Interact With Other Species’ Samples.