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Anti-LAMP-1 Rabbit Polyclonal Antibody

Dodavatel: BioVision
BIOV5077-100EA 9170 CZK
BIOV5077-100
Anti-LAMP-1 Rabbit Polyclonal Antibody
Protilátky
Autophagy, the process of bulk degradation of cellular proteins throμgh an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components and is negatively regulated by TOR (Target of rapamycin;A protein recently found to be involved in autophagy, LAMP-2, is a highly glycosylated protein associated with the lysosome. LAMP-1 shares much homology to LAMP-2 and is thoμght to have overlapping functions. Mice lacking LAMP-1 had very minor defects compared to those deficient in LAMP-2 expression. However, the loss of both proteins resulted in embryonic lethality, sμggesting that each protein possesses some unique and necessary functions.

Recommended Dilutions: Western Blot: 1 - 2 ?g/ml, Immunofluorescence: 20 ?g/ml, ELISA

Type: Primary
Antigen: LAMP-1
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG1
Reactivity: Human, Mouse, Rat
Objednat

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