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Anti-DR6 Rabbit Polyclonal Antibody

Dodavatel: BioVision
BIOV3216R-100EA 6910 CZK
BIOV3216R-100
Anti-DR6 Rabbit Polyclonal Antibody
Protilátky
Apoptosis is induced by certain cytokines including TNF and Fas ligand of the TNF family throμgh their death domain containing receptors, TNF-R1 and Fas. Several novel death receptor including DR3, DR4, and DR5 were recently identified. A new death domain containing receptor in the TNFR family was cloned recently and termed DR6 for death receptor 6. Like TNF-R1, DR6 interacts with death domain containing adapter molecule TRADD. Overexpression of DR6 induces apoptosis and activates NF-kB and JNK. DR6 is widely expressed in human tissues and cell lines.

Recommended Dilutions: Western Blot: 0.5-4 µg/ml

Type: Primary
Antigen: DR6
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
Objednat

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