Tisk…

Anti-SODD Rabbit Polyclonal Antibody

Dodavatel: BioVision
BIOV3221-100EA 7470 CZK
BIOV3221-100
Anti-SODD Rabbit Polyclonal Antibody
Protilátky
Apoptosis is induced by certain cytokines including TNF and Fas ligand of the TNF family throμgh their death domain containing receptors, TNF-R1 and Fas. Several novel death receptors including DR3, DR4, DR5, and DR6 were recently identified. Cell death signal is transduced by death domain containing adapter molecules throμgh the interaction with death domain of these death receptors. A novel TNF-R1 interacting protein was recently identified and designated SODD for silencer of death domain. SODD associates with the death domain of TNF-R1 and prevents constitutive activation of TNF-R1 signaling. TNF treatment releases SODD and permits adapter molecules such as TRADD recruiting to the active TNF-R1 complex, which activates TNF signaling pathways. SODD also interacts with DR3. SODD is ubiquitously expressed in human tissues and cell lines.

Recommended Dilutions: Western Blot: 1-2 µg/ml

Type: Primary
Antigen: SODD
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope: N-terminal
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
Objednat

Learn more

About VWR

Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...

Více About VWR