Anti-TACE Rabbit Polyclonal Antibody

Dodavatel: BioVision
BIOV3222-100EA 7900 CZK
Anti-TACE Rabbit Polyclonal Antibody
Tumor necrosis factor-α (TNF-α) is a proinflammatory cytokine and contributes to a variety of inflammatory disease responses and programmed cell death. TNF-α is synthesized as a 26K type II membrane-bound precursor that is cleaved by a convertase to generate secreted 17K mature TNF-α. TNF-α converting enzyme (TACE) protein was recently purified and the human and mouse TACE cDNAs were cloned by several groups separately. TACE is a membrane-bond metalloprotease-disintegrin in the family of mammalian ADAM (for a disintegrin and metalloprotease;TACE also processes other cell surface proteins, including TNF receptor, TGF-α, L-selectin adhesion molecule, and alpha-cleavage of amyloid protein precursor (APP;TACE mRNA is expressed in a variety of human and murine tissues.

Recommended Dilutions: Western Blot: 1-2 µg/ml

Type: Primary
Antigen: TACE
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat

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