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Anti-DAP12 Rabbit Polyclonal Antibody

Dodavatel: BioVision
BIOV5570R-100EA 7900 CZK
BIOV5570R-100
Anti-DAP12 Rabbit Polyclonal Antibody
Protilátky
DAP12 (KARAP) is a natural killer (NK) cell-expressed cell surface receptor and belongs to the immunoglobulin and C-type lectin superfamily. Unlike other members of this family which possess immunoreceptor tyrosine-based inhibitory motifs (ITIM), DAP12 contains an immunoreceptor tyrosine-based activation motif (ITAM) in its cytoplasmic domain and is present as a disulphide-bonded homodimer. Crosslinking of DAP 12-KIR complexes (membrane glycoproteins of the killer-cell inhibitory receptor family without an ITIM in their cytoplasmic domain) results in cellular activation.

Recommended Dilutions: Western Blot: 0.5-4 µg/ml

Type: Primary
Antigen: DAP12
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human
Objednat

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