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Anti-HDAC8 Rabbit Polyclonal Antibody

Dodavatel: BioVision
BIOV5618-100EA 6910 CZK
BIOV5618-100
Anti-HDAC8 Rabbit Polyclonal Antibody
Protilátky
Human Histone Deacetylase 8 (HDAC8) is a member of the class I Histone Deacetylases. HDACs are important enzymes for the transcriptional regulation of gene expression in eukaryotic cells. HDACs catalyze the removal of acetyl groups from lysines near the N-termini of histones. Human HDACs have been implicated in a variety of human diseases such as cardiomyopathy, osteodystrophy, neurodegenerative disorders, aging and cancer. Expression of HDAC8 is restricted to cells showing smooth muscle differentiation in normal human tissue and is a novel marker of smooth muscle differentiation. Like other class I and II HDAC members, the activity of HDAC8 is sensitive to HDAC inhibitor Trichostatin A (TSA).

Recommended Dilutions: Western Blot: 1-5 µg/ml

Type: Primary
Antigen: HDAC8
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human
Objednat

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