Anti-Artemis Rabbit Polyclonal Antibody

Dodavatel: BioVision
BIOV3307-100EA 7470 CZK
Anti-Artemis Rabbit Polyclonal Antibody
Artemis is a 78 kDa protein, belonging to metallo-beta-lactamase superfamily. It is involved in endonuclease activity to break DNA hairpins. It also has been reported that the C-terminus of Artemis interacts with DNA binding domain of Ligase IV directly. Ligase IV is a key enzyme in DNA repair and V(D)J recombination. Thus, Artemis is a novel protein that is involved in V(D)J recombination/DNA repair. Mutations cause human T-B-severe combined immunodeficiency associated with increased cellular radiosensitivity (RS-SCID).

Recommended Dilutions: Western Blot: 1:200

Type: Primary
Antigen: Artemis
Clonality: Polyclonal
Conjugation: Unconjugated
Epitope: C-terminal
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat

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