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Anti-IGF-BP3 Rabbit Polyclonal Antibody

Dodavatel: BioVision
BIOV5720-200EA 6910 CZK
BIOV5720-200
Anti-IGF-BP3 Rabbit Polyclonal Antibody
Protilátky
Human IGF-BP3, also known as growth-hormone-dependant binding protein, is a 28.9 kDa cysteine-rich secreted protein. It is the major IGF binding protein present in the plasma of human and animals. In addition to its ability to modulate the activity of IGF-I and IGF-2, IGF-BP3 also exerts inhibitory effects on follicle stimulating hormone (FSH) activity. Decreased plasma levels of IGF-BP3 often results in dwarfism, whereas elevated levels of IGF-BP3 may lead to acromegaly. The expression of IGF-BP3 in fibroblasts is stimulated by mitogenic growth factors such as Bombesin, Vasopressin, PDGF, and EGF.

Recommended Dilutions: Western Blot: 2-6 µg/ml

Type: Primary
Antigen: IGF-BP3
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human
Objednat

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