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Anti-Procathepsin K Rabbit Polyclonal Antibody

Dodavatel: BioVision
BIOV6661-100EA 7470 CZK
BIOV6661-100
Anti-Procathepsin K Rabbit Polyclonal Antibody
Protilátky
Cathepsin K, a member of the papain cysteine proteinase family, is the predominant proteinase responsible for the resorption of the bone matrix. Cathepsin cleaves proteins such as collagen type I, collagen type II and osteonectin, thereby playing a role in bone remodeling and resorption in osteoporosis, osteolytic bone metastasis and rheumatoid arthritis (Bromme and Okamoto, 1995; Drake, F. et al 1996; Bossard et al, 1996;Cathepsin K is produced as an inactive proenzyme (35.4 kDa) that is converted to its mature active form (23.5 kDa) by proteolytic cleavage of its 99-amino-acid propeptide domain. The in-vitro processing of Procathepsin K to mature Cathepsin K is autocatalytic.

Recommended Dilutions: Western Blot: 1-4 µg/ml.

Type: Primary
Antigen: Procathepsin K
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Rat
Objednat

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