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Anti-NPM Rabbit Polyclonal Antibody

Dodavatel: BioVision
BIOV3425-100EA 7470 CZK
BIOV3425-100
Anti-NPM Rabbit Polyclonal Antibody
Protilátky
NPM (Nucleophosmin) is an abundant phosphoprotein primarily found in nucleoli. It has been implicated in several distinct cellular functions, including assembly and transport of ribosomes, cytoplasmic/nuclear trafficking, regulation of DNA polymerase alpha activity, centrosome duplication and molecular chaperoning activities. The NPM gene is also known for its fusion with the anaplastic lymphoma kinase (ALK) receptor tyrosine kinase. The NPM portion contributes to transformation by providing a dimerization domain, which results in activation of the fused kinase.

Recommended Dilutions: Western Blot: 1-2 µg/ml; Immunohistochemistry: 10-20 µg/ml

Type: Primary
Antigen: NPM
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope: N-terminal
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
Objednat

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