Anti-MSH2 Rabbit Polyclonal Antibody

Dodavatel: BioVision
BIOV3429-100EA 9730 CZK
Anti-MSH2 Rabbit Polyclonal Antibody
DNA mismatch repair genes have been found to be associated with hereditary nonpolyposis colorectal cancer (HNPCC;Inherited mutations in the MSH2 were demonstrated at high frequency in HNPCC and were shown to be associated with microsatellite instability. The demonstration that 10 to 45% of pancreatic, gastric, breast, ovarian and small cell lung cancers also display microsatellite instability sμggests that DNA mismatch repair is not restricted to HNPCC tumors but is a common feature in tumor initiation or progression.

Recommended Dilutions: Western Blot: 1-4 µg/ml; Immunoprecipitation: 15-25 µg/ml; and Immunohistochemistry: 15-25 µg/ml

Type: Primary
Antigen: MSH2
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat

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