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Anti-LIMK1 Rabbit Polyclonal Antibody

Dodavatel: BioVision
BIOV3433-100EA 7470 CZK
BIOV3433-100
Anti-LIMK1 Rabbit Polyclonal Antibody
Protilátky
LIM kinases (LIMK1 and LIMK2) are serine/threnine kinases that have two zinc finger motifs, known as LIM motifs in their N-terminal regulatory domain. LIM kinases are involved in actin cytoskeleton regulation throμgh Rho-family GTPases and downstream kinases PAKs and ROCK. PAK1 and ROCK phosphorylate LIMK1 and LIMK2, which increases the activity of the kinases. Activated LIM kinases inhibit the actin depolymerization activity of cofilin by phosphorylation at the N-terminus of Cofilin.

Recommended Dilutions: Western Blot: 1-4 µg/ml

Type: Primary
Antigen: LIMK1
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope: C-terminal
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
Objednat

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