Anti-uPAR Goat Polyclonal Antibody

Dodavatel: BioVision
BIOV3440-100EA 8320 CZK
Anti-uPAR Goat Polyclonal Antibody
uPAR (Urokinase plasminogen activator receptor) is a 55 kDa glycoprotein I-anchored surface receptor specific for urokinase plasminogen activator (uPA;Upon binding to uPAR, uPA converts the surface bound, large serum β-globulin, plasminogen to plasmin. Plasmin, which is also designated fibrinolysin, is a trypsin-like enzyme that acts on Arg-Lys bonds and induces pericellular proteolysis in fibrin and fibrinogen, and thereby contributes to the systematic activation of the coagulation cascade. uPA and uPAR are known to be overexpressed in mesenchymal and epithelial tumor cells and are required for tumor invasion and metastasis.

Recommended Dilutions: Western Blot: 0.5-2 µg/ml; Immunoprecipitation: 5-10 µg/ml; Neutralization: 2-4 µg/ml

Type: Primary
Antigen: uPAR
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Goat
Isotype: IgG
Reactivity: Human

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