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Human Recombinant SLIT2-N

Dodavatel: Tonbo Biosciences
21-7132-U005EA 1990 CZK
21-7132-U005 21-7132-U500 21-7132-U100 21-7132-U025
Human Recombinant SLIT2-N
Proteiny
Slit2 belongs to the Slit family of proteins that, along with the Roundabout (Robo) family of receptors, act as guidance cues for cellular migration. In mammals, there are 3 known Slit proteins and 4 Robo receptors. Slit2 associates with Robo1 to contribute to various functions including leukocyte chemotaxis, angiogenesis, neuronal migration and mediating repulsive cues in axon guidance. It has also been reported to inhibit tumor growth and migration in certain types of cancers. Slit2 is initially synthesised as a precursor protein which is subsequently cleaved into N-terminal (Slit2-N) and C-terminal (Slit2-C) fragments. Slit2-N is the larger protein and is associated with neurodevelopment-related activities.
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