Human recombinant SCD100

Dodavatel: Tonbo Biosciences
21-7144-U100EA 23530 CZK
TNBO21-7144-U100 TNBO21-7144-U005 TNBO21-7144-U500 TNBO21-7144-U020
Human recombinant SCD100
CD100, also known as Sema4D, is a transmembrane protein belonging to the Class IV subfamily of Semaphorins. CD100 is active as a homodimer, however cleavage by certain metalloproteinases produce a soluble dimer that is also active. It is expressed on T and B cells, as well as macrophages, and with upregulated expression on activated T cells. CD100 plays important roles in immune and inflammatory responses, being involved in B cell and dendritic cell activation. It also induces B cells to aggregate and may improve their viability. CD72 is one of 2 known receptors for CD100 and binding of the ligand to this receptor is reported to be an important factor in maintaining immunological homeostasis.

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