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Anti-MST1R Rabbit Polyclonal Antibody

Dodavatel: ProSci Inc.
MST1R/Ron, a HGF Receptor/MET-type protein kinase, mediates the biological activities of macrophage-stimulating protein (MSP), a multifunctional cytokine that regulates cell adhesion, motility, growth, and survival. The protein is a membrane-spanning, disulfide-linked heterodimer, which results from cleavage of a glycosylated precursor into 35-kD (alpha) and 150-kD (beta) subunits. Ligand binding results in tyrosine phosphorylation of the beta chain. In knockout studies, MST1R/RON (-/-) mice failed to survive past the periimplantation period. The MST1R/RON gene has been mapped to 3p21, a region of frequent deletion or mutation in small cell lung and renal carcinoma, and has been implicated in the progression of several epithelial cancers.

MST1R antibody can be used in immunohistochemistry starting at 20 μg/mL, and immunofluorescence.

PBS, 0.1% sodium azide.

PBS, 0.1% sodium azide.

Aliquot and store at -80°C. Avoid multiple freeze-thaw cycles.

Type:
Antigen: MST1R
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype:
Reactivity: Bat, Gorilla, Human, Monkey



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OBJEDNÁVKA

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Rozměry protilátky Bal. VWR katalogové číslo Množství
50 µg 50 µG PRSI48-321
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TECHNICKÉ ÚDAJE

Symbol antigenu MST1R
Název antigenu Macrophage Stimulating 1 Receptor
Reaktivita Monkey, Gorilla, Bat, Human
Spojení Unconjugated
Klonovalita Polyclonal
Hostitel Rabbit
Imunochemie Yes
Synonyma antigenu soluble RON variant 2, soluble RON variant 3, CD136, MST1R variant RON62, RON, MSP receptor, soluble RON variant 1, c-met-related tyrosine kinase, macrophage-stimulating protein receptor, p185-Ron, soluble R, PTK8 protein tyrosine kinase 8, RON variant E2E3, CDw136, PTK8, MST1R variant RON30
Imunogen MST1R antibody was raised against a peptide located near the internal domain of MST1R (Human).
Forma Liquid
Testované aplikace Immunoaffinity Chromatography
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