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Benzo[a]pyren ≥96% (by HPLC), Sigma-Aldrich®

Dodavatel: Merck
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M-Clarity™ quality level = MQ200

SIALB1760-5GEA 0 CZK
SIALB1760-5G SIALB1760-1G SIALB1760-100MG SIALB1760-250MG SIALB1760-500MG
Benzo[a]pyren ≥96% (by HPLC), Sigma-Aldrich®
Benzo[a]pyren

Benzo[a]pyrene (PAH), a polycyclic aromatic hydrocarbon pollutant, is used as a chemical carcinogen in experimental models of cancer.


Carcinogenesis depends on it′s oxidation by CYP1A1 to benzo[a]pyrenediolepoxide, that forms depurinating adducts with DNA that dissociate to form abasic lesions. Benzo[a]pyrene is a ligand for the arylhydrocarbon receptor (AhR), and some of its biological effects, including the induction of CYP1A1, appear to be mediated via activation of the AhR.

Vzorec: C₂₀H₁₂
MW: 252,32 g/mol
Bod varu: 495 °C (1013 hPa)
Bod tání: 176…178 °C
Hustota: 1,351 g/cm³ (20 °C)
MDL Number: MFCD00003602
CAS číslo: 50-32-8
EINECS: 200-028-5
UN: 2811
ADR: 6.1,III
Merck Index: 12,01134

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